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E-AB-17161

TRPC4AP Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:
E-AB-17161
Additional Names:
TRPC4AP,C20orf188,Chromosome 20 open reading frame 188,Protein TAP1,Protein TRUSS,Short transient receptor potential channel 4 associated protein,Short transient receptor potential channel 4-associated protein,TAP1 protein,TNF receptor ubiquitous scaffol
Application:
IHC
Concentration:
0.9 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Fusion protein of human TRPC4AP
Uniprot:
Q8TEL6
Synonyms:
C20orf188;PPP1R158;protein phosphatase 1, regulatory subunit 158;Protein TAP1;short transient receptor potential channel 4-associated protein;TNF-receptor ubiquitous scaffolding/signaling protein;TRP4-associated protein;trpc4-associated protein;TRRP4AP;TRUSS;tumor necrosis factor receptor-associated ubiquitous scaffolding and signaling protein
Extra Details:
TRPC4AP (transient receptor potential cation channel, subfamily C, member 4 associated protein), also known as TRUSS or TRRP4AP, is a 797 amino acid protein that is expressed in a variety of tissues, with highest expression in liver, heart, testis and brain. Thought to function as a scaffolding protein, TRPC4AP interacts with TNF-R1 and may both link TNF-R1 to the IKK signalsome complex, and participate in the activation of NFK KappaB p50, an event that occurs in response to TNF-R1 ligation. TRPC4AP exists as multiple alternatively spliced isoforms that are encoded by a gene whicHuman, Mouseaps to human chromosome 20. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome.
Shipping Conditions:
Blue Ice