E-AB-17147
TRIB2 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-17147
- Additional Names:
- C5FW,FLJ57420,GS3955,Hypothetical protein TRB2,TRB-2,TRB2,TRIB 2,TRIB2,Tribbles homolog 2
- Application:
- IHC
- Concentration:
- 0.4 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Full length fusion protein
- Uniprot:
- Q92519
- Synonyms:
- C5FW;GS3955;TRB2;tribbles homolog 2
- Extra Details:
- This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene.
- Shipping Conditions:
- Blue Ice