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E-AB-17130

TPX2 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-17130
Additional Names:
C20ORF1,C20orf2,Chromosome 20 Open Reading Frame 1,Differentially expressed i,Differentially expressed in cancerous and non-cancerous lung cells 2,Differentially expressed in cancerous and noncancerous lung cells 2,Differentially expressed in lung cells 2
Application:
IHC, WB
Concentration:
0.7 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Fusion protein of human TPX2
Uniprot:
Q9ULW0
Synonyms:
C20orf1;C20orf2;differentially expressed in cancerous and non-cancerous lung cells 2;differentially expressed in lung cells;DIL-2;DIL2;FLS353;GD:C20orf1;HCA519;HCTP4;hepatocellular carcinoma-associated antigen 519;hepatocellular carcinoma-associated antigen 90;p100;preferentially expressed in colorectal cancer;protein fls353;REPP86;restricted expression proliferation associated protein 100;Restricted expression proliferation-associated protein 100;targeting protein for Xklp2;TPX2, microtubule-associated protein homolog;TPX2, microtubule-associated, homolog
Extra Details:
Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation.
Shipping Conditions:
Blue Ice