E-AB-17096
TIRAP Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-17096
- Additional Names:
- Adapter protein wyatt,FLJ42305,MAL,MyD88 adapter like protein,TIR domain containing adapter protein,Toll interleukin 1 receptor (TIR) domain containing adaptor protein,Toll interleukin 1 receptor domain containing adapter protein,Toll like receptor adapto
- Application:
- IHC
- Concentration:
- 0.5 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Full length fusion protein
- Uniprot:
- P58753
- Synonyms:
- adapter protein wyatt;adaptor protein Wyatt;BACTS1;Mal;MyD88 adapter-like protein;MyD88-2;toll-interleukin 1 receptor (TIR) domain containing adaptor protein;Toll-like receptor adaptor protein;toll/interleukin-1 receptor domain-containing adapter protein;wyatt
- Extra Details:
- The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns.Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction.The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system.It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response.Alternative splicing of this gene results in several transcript variants, however, not all variants have been fully described.
- Shipping Conditions:
- Blue Ice