E-AB-16974
AIF1 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-16974
- Additional Names:
- AIF 1,AIF-1,AIF1,AIF1 protein,Aif1,Allograft inflammatory factor 1,Allograft inflammatory factor 1 splice variant G,BART 1,G1,G1 putative splice variant of ,allograft inflammatory factor-1 splice variant Hara-1,balloon angioplasty responsive transcription
- Application:
- IHC
- Concentration:
- 0.7 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Full length fusion protein
- Uniprot:
- P55008
- Synonyms:
- AIF-1;allograft inflammatory factor 1;IBA1;interferon gamma responsive transcript;ionized calcium-binding adapter molecule 1;IRT-1;IRT1;protein G1
- Extra Details:
- This gene is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. Three transcript variants encoding different isoforms have been found for this gene. ,Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
- Shipping Conditions:
- Blue Ice