E-AB-16795
SDHB Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-16795
- Additional Names:
- CWS2,DHSB,FLJ92337,Ip,Iron sulfur subunit,Iron sulfur subunit of complex II,Iron-sulfur subunit of complex II,PGL 4,PGL4,SDH,SDH 1,SDH1,SDH2,SDHIP,SdhB,Su,Succinate dehydrogenase [ubiquinone] iron sulfur protein mitochondrial,homolog of,mitochondrial
- Application:
- IHC, WB
- Concentration:
- 0.4 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human SDHB
- Uniprot:
- P21912
- Synonyms:
- CWS2;IP;iron-sulfur subunit of complex II;MC2DN4;PGL4;SDH;SDH1;SDH2;SDHIP;succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial;succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
- Extra Details:
- Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
- Shipping Conditions:
- Blue Ice