E-AB-16715
PNN Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-16715
- Additional Names:
- 140 kDa nuclear and cell adhesion-related phosphoprotein,DRS,DRS protein,DRSP,Desmosome-associated protein,Domain-rich serine protein,MEMA,Melanoma metastasis clone A protein,Nuclear protein SDK3,PININ,PNN,Pinin,SR like protein,SR-like protein
- Application:
- IHC
- Concentration:
- 1.2 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human PNN
- Uniprot:
- Q9H307
- Synonyms:
- 140 kDa nuclear and cell adhesion-related phosphoprotein;desmosome-associated protein;domain-rich serine protein;DRS;DRSP;melanoma metastasis clone A protein;memA;neutrophil protein;nuclear protein SDK3;pinin;SDK3;SR-like protein
- Extra Details:
- Pinin is a desmosomal associated protein involved with the maintenance of cell to cell adhesion of the epithelium. Pinin is a widespread protein and has been shown to play an important role in cell adhesion through its interaction with nuclear complexes. Pinin is also involved in pre-mRNA splicing through its interactions with a C-terminal RS domain of Cyclophilin G, a Moca type nuclear cyclophilin. Pinin becomes nuclear during the early stages of embryonic development and remains so throughout the entire period. Defects or lack of Pinin can be lethal at perinatal stages and causes defects in the cardiac outflow tract, axial skeleton, palate and dorsal dermis.
- Shipping Conditions:
- Blue Ice