E-AB-16657
NPHS2 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-16657
- Additional Names:
- NPHS2,NPHS2 gene,Nephrosis 2,PDCN,PODO,Podocin,SRN1,idiopathic,nephrosis 2,steroid resistant,steroid resistant (podocin)
- Application:
- IHC
- Concentration:
- 1.4 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human NPHS2
- Uniprot:
- Q9NP85
- Synonyms:
- nephrosis 2, idiopathic, steroid-resistant (podocin);NPHS2, podocin;PDCN;podocin;SRN1
- Extra Details:
- This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined.
- Shipping Conditions:
- Blue Ice