E-AB-16648
NLRP10 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-16648
- Additional Names:
- CLR11.1,LRR and PYD domains containing protein 10,LRR and PYD domains-containing protein 10,NACHT,NAL10,NALP10,NLR family,NOD8,Nlrp10,Nucleotide-binding oligomerization domai,leucine rich repeat and PYD containing 10,pyrin domain containing 10
- Application:
- IHC
- Concentration:
- 1.2 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human NLRP10
- Uniprot:
- Q86W26
- Synonyms:
- CLR11.1;NACHT, leucine rich repeat and PYD containing 10;NACHT, LRR and PYD domains-containing protein 10;NALP10;NOD8;nucleotide-binding oligomerization domain protein 8;nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 10;PAN5;PYNOD
- Extra Details:
- Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis.
- Shipping Conditions:
- Blue Ice