E-AB-16621
MT-ND1 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-16621
- Additional Names:
- Complex I,MT-ND1,MTND1,Mitochondrially encoded NADH dehydrogenase 1,NAD1,NADH dehydrogenase subunit 1,NADH dehydrogenase subunit 1 (complex I),NADH-ubiquinone oxidoreductase,NADH-ubiquinone oxidoreductase chain 1,NADH1,ND1,NU1M,subunit ND1
- Application:
- IHC
- Concentration:
- 0.6 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human MT-ND1
- Uniprot:
- P03886
- Synonyms:
- MTND1;NADH dehydrogenase subunit 1
- Extra Details:
- NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by translocation of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 1 (ND1) binds rotenone and rotenone analogs and might be involved in electron transfer to ubiquinone. Mutations in the ND1 gene may be implicated in several disorders, including Leber hereditary optic neuropathy, Alzheimer disease, and Parkinson disease.
- Shipping Conditions:
- Blue Ice