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E-AB-16563

UBP1 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-16563
Additional Names:
LBP-1B,LBP-1a,LBP1A,LBP1B
Application:
IHC, WB
Concentration:
0.7 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human UBP1
Uniprot:
Q9NZI7
Synonyms:
LBP-1a;LBP-1B;LBP1A;LBP1B;transcription factor LBP-1;upstream-binding protein 1
Extra Details:
LBP1 (Upstream-binding protein 1), also designated UBP1, LBP1A or LBP1B, is a 540 amino acid protein that belongs to the grh/CP2 family (grainyhead transcription factor family).LBP1 is a transcriptional activator that regulates the placental expression of CYP11A1 and activates the Hemoglobin globin promoter in erythroid cells.LBP1 is responsible for repressing transcription of HIV-1 by binding to and preventing TFIID from interacting with its promoter region.Null expression of LBP1 causes uterine growth retardation in mice embryos suggesting a critical role in extraembryonic angiogenesis.
Shipping Conditions:
Blue Ice