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E-AB-16515

IL5RA Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:
E-AB-16515
Additional Names:
CDw,HSIL5R,IL5RA,CD125,CDw125,HSIL5R3,IL5R,IL-5 receptor subunit alpha,IL-5R subunit alpha,IL-5RA,IL-5R-alpha,Interleukin-5 receptor subunit alpha, CDw125,IL-5R&amp,alpha,CD125 antigen,IL5R,Interleukin 5 Receptor alpha,Interleukin 5 Receptor alpha chain,Interleukin 5 receptor alpha subunit,Interleukin 5 receptor subunit alpha,Interleukin 5 receptor type 3,MGC26560
Application:
IHC, WB
Concentration:
0.9 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human IL5RA
Uniprot:
Q01344
Synonyms:
CD125;CD125 antigen;CDw125;HSIL5R3;IL-5 receptor subunit alpha;IL-5R subunit alpha;IL5R;interleukin 5 receptor type 3;interleukin 5 receptor, alpha;interleukin-5 receptor alpha chain;interleukin-5 receptor subunit alpha
Extra Details:
The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.
Shipping Conditions:
Blue Ice