E-AB-16491
NRG1 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-16491
- Additional Names:
- ARIA,Acetylcholine receptor-inducing activity,Breast cancer cell differentiation factor p45,CHICK,ERBB2 p185-activator),GGF,GGF2,Glial growth factor,HGL,HRG,HRG1,HRGA,Heregulin,MST1,alpha (45kD,heregulin,homolog of
- Application:
- IHC, WB
- Concentration:
- 0.6 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human NRG1
- Uniprot:
- Q02297
- Synonyms:
- acetylcholine receptor-inducing activity;ARIA;GGF;GGF2;glial growth factor 2;heregulin, alpha (45kD, ERBB2 p185-activator);HGL;HRG;HRG1;HRGA;MST131;MSTP131;NDF;neu differentiation factor;NRG1-IT2;pro-neuregulin-1, membrane-bound isoform;pro-NRG1;sensory and motor neuron derived factor;SMDF
- Extra Details:
- The protein encoded by this gene was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. This protein is a signaling protein that mediates cell-cell interactions and plays critical roles in the growth and development of multiple organ systems. It is known that an extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are tissue-specifically expressed and differ significantly in their structure, and thereby these isoforms are classified into types I, II, III, IV, V and VI. The gene dysregulation has been linked to diseases such as cancer, schizophrenia and bipolar disorder (BPD).
- Shipping Conditions:
- Blue Ice