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E-AB-16488

HRG Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-16488
Additional Names:
DKFZp779H1622,HPRG,HRGP,Histidine proline rich glycoprotein,Histidine rich glycoprotein,Thrombophilia due to elevated HRG
Application:
IHC
Concentration:
1.1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human HRG
Uniprot:
P04196
Synonyms:
histidine-proline-rich glycoprotein;histidine-rich glycoprotein;HPRG;HRGP;THPH11
Extra Details:
This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.
Shipping Conditions:
Blue Ice