E-AB-16474
HACE1 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-16474
- Additional Names:
- E3 ubiquitin-protein ligase HACE1,HACE 1,HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1,KIAA1320
- Application:
- IHC
- Concentration:
- 1.5 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human HACE1
- Uniprot:
- Q8IYU2
- Synonyms:
- E3 ubiquitin-protein ligase HACE1;HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1;HECT-type E3 ubiquitin transferase HACE1;SPPRS
- Extra Details:
- HACE1 (HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1), also known as KIAA1320, is a 909 amino acid protein that localizes to both the cytoplasm and the endoplasmic reticulum and contains one HECT domain and six ANK repeats. Expressed in kidney, heart and brain, HACE1 functions as an E3 ubiquitin-protein ligase that interacts with the proteasome and is thought to play a role in protein degradation. HACE1 is downregulated in Wilms tumor, suggesting a possible role in tumor suppression.
- Shipping Conditions:
- Blue Ice