E-AB-16322
CD54 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-16322
- Additional Names:
- Antigen identified by monoclonal BB2,BB 2,BB2,CD 54,CD54,CD_antigen=CD54,Cell surface glycoprotein P3.58,Human rhinovirus receptor,ICAM 1,ICAM-1,ICAM1,Intercellular adhesion molecule,human rhinovirus receptor,intercellular adhesion molecule 1 (CD54)
- Application:
- IHC, WB
- Concentration:
- 0.4 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human ICAM1
- Uniprot:
- P05362
- Synonyms:
- BB2;CD54;cell surface glycoprotein P3.58;epididymis secretory sperm binding protein;ICAM-1;intercellular adhesion molecule 1;intercellular adhesion molecule 1 (CD54), human rhinovirus receptor;major group rhinovirus receptor;P3.58
- Extra Details:
- This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
- Shipping Conditions:
- Blue Ice