E-AB-16318
CD40 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-16318
- Additional Names:
- AI326936,B cell associated molecule CD40,B cell surface antigen CD40,B cell-associated molecule,B-cell surface antigen CD40,Bp50,CD 40,CD40,CD40 antigen,CD40 antigen (TNF receptor superfamily member 5),CD40 molecule,TNF receptor superfamily
- Application:
- IHC
- Concentration:
- 1.3 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human CD40
- Uniprot:
- P25942
- Synonyms:
- B cell surface antigen CD40;B cell-associated molecule;B-cell surface antigen CD40;Bp50;CD40 molecule, TNF receptor superfamily member 5;CD40L receptor;CDW40;p50;TNFRSF5;tumor necrosis factor receptor superfamily member 5
- Extra Details:
- The protein encoded by this gene is a member of the TNF-receptor superfamily.This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation.AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, whicHuman, Mouseay be important for homotypic cell interactions.Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction.The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis.
- Shipping Conditions:
- Blue Ice