E-AB-16309
CD2AP Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-16309
- Additional Names:
- AL024079,Adapter protein CMS,C78928,CD2 associated protein,CD2-associated protein,CD2AP,CMS,Cas ligand with multiple SH3 domains,METS 1,Mesenchyme to epithelium transition protein with SH3 domains 1,Mets1
- Application:
- IHC, WB
- Concentration:
- 0.2 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human CD2AP
- Uniprot:
- Q9Y5K6
- Synonyms:
- adapter protein CMS;cas ligand with multiple SH3 domains;Cas ligand with multiple Src homology 3 (SH3) domains;CD2-associated protein;CMS
- Extra Details:
- This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.
- Shipping Conditions:
- Blue Ice