E-AB-16300
NOD1 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-16300
- Additional Names:
- CARD 4,CARD4,CLR 7.1,CLR7.1,Caspase recruitment domain 4,Caspase recruitment domain containing protein 4,Caspase recruitment domain family member 4,Caspase recruitment domain protein 4,Caspase recruitment domain-containing protein 4,NLR family CARD domain
- Application:
- IHC
- Concentration:
- 0.8 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human NOD1
- Uniprot:
- Q9Y239
- Synonyms:
- CARD4;caspase recruitment domain family, member 4;caspase recruitment domain-containing protein 4;CLR7.1;NLR family, CARD domain containing 1;NLRC1;nucleotide-binding oligomerization domain-containing protein 1;nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 1
- Extra Details:
- This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid.
- Shipping Conditions:
- Blue Ice