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E-AB-16283

BOD1 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-16283
Additional Names:
BOD1,Biorientation defective 1,Biorientation defective protein 1,Biorientation of chromosomes in cell division protein 1,FAM44B,Protein FAM44B,biorientation of chromosomes in cell division 1,family with sequence similarity 44,member B
Application:
IHC
Concentration:
0.7 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human BOD1
Uniprot:
Q96IK1
Synonyms:
biorientation defective 1;Biorientation defective protein 1;biorientation of chromosomes in cell division protein 1;FAM44B;family with sequence similarity 44, member B;Protein FAM44B
Extra Details:
Bod1, a protein conserved throughout metazoans that associates with a large macromolecular complex and localizes with kinetochores and spindle poles during mitosis.Bod1-depleted cells form syntelic attachments that can oscillate and generate enough force to separate sister kinetochores, suggesting that microtubule-kinetochore interactions were intact.Releasing Bod1-depleted cells from a monastrol block increases the frequency of syntelic attachments and the number of cells displaying biorientation defects.
Shipping Conditions:
Blue Ice