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E-AB-16268

ATP7A Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-16268
Additional Names:
ATP 7A,ATP7A,ATPase Cu++ transporting alpha polypeptide,ATPase Cu++ transporting alpha polypeptide (Menkes syndrome),ATPase copper transporting alpha polypeptide,Copper pump 1,Copper transporting ATPase 1,Copper-transporting ATPase 1,Cu++ transporti
Application:
IHC
Concentration:
0.5 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human ATP7A
Uniprot:
Q04656
Synonyms:
ATPase, Cu++ transporting, alpha polypeptide;copper pump 1;copper-transporting ATPase 1;Cu++-transporting P-type ATPase;DSMAX;Menkes disease-associated protein;MK;MNK;SMAX3
Extra Details:
This gene encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital horn syndrome. Alternatively-spliced transcript variants have been observed.
Shipping Conditions:
Blue Ice