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E-AB-16230

L1CAM Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-16230
Additional Names:
Antigen identified by monoclonal R1,CAML1,CD171,CD171 antigen,HSAS,HSAS1,Hyd,L1,L1 cell adhesion molecule,L1-NCAM,L1CAM,L1cam,MASA,MIC5,N CAML1,N-CAM-L1,NCAM-L1,NCAML1,Nerve-growth factor-inducible large external glycoprotein,Neural cell adhesion molecule
Application:
IHC
Concentration:
0.3 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human L1CAM
Uniprot:
P32004
Synonyms:
antigen identified by monoclonal antibody R1;CAML1;CD171;HSAS;HSAS1;MASA;MIC5;N-CAM-L1;N-CAML1;NCAM-L1;neural cell adhesion molecule L1;S10;SPG1
Extra Details:
The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons.
Shipping Conditions:
Blue Ice