E-AB-16196
DDAH1 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-16196
- Additional Names:
- DDAH,DDAH I,DDAH-1,DDAH1,DDAHI,Dimethylargininase 1,Dimethylargininase-1,Dimethylarginine dimethylaminohydrolase 1,N(G),N(G)-dimethylarginine dimethylaminohydrolase 1,NG NG dimethylarginine dimethylaminohydrolase
- Application:
- IHC
- Concentration:
- 0.2 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human DDAH1
- Uniprot:
- O94760
- Synonyms:
- DDAH;DDAH-1;DDAHI;dimethylargininase-1;epididymis secretory protein Li 16;HEL-S-16;N(G),N(G)-dimethylarginine dimethylaminohydrolase 1;NG, NG-dimethylarginine dimethylaminohydrolase
- Extra Details:
- This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation. DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues.
- Shipping Conditions:
- Blue Ice