E-AB-16168
API5 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-16168
- Additional Names:
- AAC 11,AAC-11,AAC11,API 5,API-5,API5,API5 like 1,API5L1,Antiapoptosis clone 11 protein,Apoptosis inhibitor 5,Cell migration inducing gene 8 protein,Cell migration-inducing gene 8 protein,Fibroblast grow,Fibroblast growth factor 2 interacting factor 2,api5
- Application:
- WB
- Concentration:
- 1.1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human API5
- Uniprot:
- Q9BZZ5
- Synonyms:
- AAC-11;AAC11;antiapoptosis clone 11 protein;apoptosis inhibitor 5;cell migration-inducing gene 8 protein;Fibroblast growth factor 2-interacting factor;fibroblast growth factor 2-interacting factor 2;FIF;migration-inducing protein MIG8;Protein XAGL
- Extra Details:
- This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
- Shipping Conditions:
- Blue Ice