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E-AB-16154

ADRA1B Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-16154
Additional Names:
ADA1B,ADRA 1,ADRA1,ADRA1B,Adra 1b,Adrenergic alpha 1B receptor,Adrenergic receptor alpha 1b,Adrenoceptor alpha 1B,Alpha 1 adrenergic receptor,Alpha 1B adrenoceptor,Alpha 1B adrenoreceptor,Alpha-1B adrenergic receptor,Alpha-1B adreno,Alpha-1B adrenoceptor
Application:
WB
Concentration:
0.2 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human ADRA1B
Uniprot:
P35368
Synonyms:
ADRA1;adrenergic, alpha-1B-, receptor;alpha-1B adrenergic receptor;alpha-1B adrenoceptor;alpha-1B adrenoreceptor;ALPHA1BAR
Extra Details:
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.
Shipping Conditions:
Blue Ice