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E-AB-16147

ALDH5A1 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-16147
Additional Names:
ALDH5A 1,Aldedehyde dehydrogenase 5 family,Aldehyde dehydrogenase 5 family member A1,Aldehyde dehydrogenase 5A1,Aldehyde dehydrogenase family 5 member A1,Aldh5a1,Mitochondrial succinate semialdehyde dehydrogenase,NAD(+) dependent succinic se,mitochondrial
Application:
IHC
Concentration:
0.4 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human ALDH5A1
Uniprot:
P51649
Synonyms:
Aldehyde dehydrogenase family 5 member A1;mitochondrial succinate semialdehyde dehydrogenase;NAD(+)-dependent succinic semialdehyde dehydrogenase;SSADH;SSDH;succinate-semialdehyde dehydrogenase, mitochondrial
Extra Details:
This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.
Shipping Conditions:
Blue Ice