SIPA1 Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:: E-AB-16071
Additional Names:: GTPase activating protein Spa 1,GTPase-activating protein Spa-1,MGC102688,MGC17037,Signal induced proliferation associated 1,Signal induced proliferation associated gene 1,Signal induced proliferation associated protein 1,Signal-induc,p130 SPA-1,p130 SPA1
Application:: IHC
Concentration:: 0.4 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Synthetic peptide of human SIPA1
Uniprot:: Q96FS4
Synonyms:: GTPase-activating protein Spa-1;p130 SPA-1;signal-induced proliferation-associated gene 1;signal-induced proliferation-associated protein 1;sipa-1;SPA1
Extra Details:: The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date.