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E-AB-16064

SLC27A1 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-16064
Additional Names:
ACSVL5,FATP,FATP 1,FATP1,FLJ00336,Fatty acid transport protein 1,Long chain fatty acid transport protein 1,MGC71751,SLC27A1,Solute carrier family 27 (fatty acid transporter) member 1,Solute carrier family 27 member 1
Application:
IHC
Concentration:
0.2 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human SLC27A1
Uniprot:
Q6PCB7
Synonyms:
ACSVL5;FATP;FATP-1;FATP1;fatty acid transport protein 1;long-chain fatty acid transport protein 1;solute carrier family 27 (fatty acid transporter), member 1;Solute carrier family 27 member 1
Extra Details:
The protein involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. The LFCA import appears to be hormone-regulated in a tissue-specific manner. In adipocytes, but not myocytes, insulin induces a rapid translocation of FATP1 from intracellular compartments to the plasma membrane, paralleled by increased LFCA uptake. Plays a pivotal role in regulating available LFCA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids .Highest levels of expression are detected in muscle and adipose tissue small, intermediate levels in small intestine, and barely detectable in liver.
Shipping Conditions:
Blue Ice