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E-AB-15993

NDRG1 Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:
E-AB-15993
Additional Names:
42 kDa,Anti GC4,DRG-1,Differentiation related gene1 protein,Differentiation-related gene 1 protein,Drg 1,GC4,Human mRNA for RTP complete cds,N myc downstream regulated gene 1,N myc downstream regulated gene 1 protein,N-myc downs,cap43,cmt4d,drg1,gc4,hmsnl
Application:
IHC, WB
Concentration:
0.6 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human NDRG1
Uniprot:
Q92597
Synonyms:
CAP43;CMT4D;differentiation-related gene 1 protein;DRG-1;DRG1;GC4;HMSNL;N-myc downstream-regulated gene 1 protein;NDR1;nickel-specific induction protein Cap43;NMSL;protein NDRG1;protein regulated by oxygen-1;PROXY1;reducing agents and tunicamycin-responsive protein;RIT42;RTP;TARG1;TDD5
Extra Details:
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Shipping Conditions:
Blue Ice