E-AB-15942
LATS2 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-15942
- Additional Names:
- FLJ13161,KPM,Kinase phosphorylated during mitosis protein,L,LATS large tumor suppressor Drosophila homolog 2,LATS large tumor suppressor homolog 2,Large tumor suppressor homolog 2,Large tumor suppressor homolog 2 Drosophila,Large tumor suppressor kinase 2
- Application:
- IHC
- Concentration:
- 0.5 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human LATS2
- Uniprot:
- Q9NRM7
- Synonyms:
- kinase phosphorylated during mitosis protein;KPM;large tumor suppressor homolog 2;LATS (large tumor suppressor, Drosophila) homolog 2;LATS, large tumor suppressor, homolog 2;serine/threonine kinase KPM;serine/threonine-protein kinase kpm;serine/threonine-protein kinase LATS2;warts-like kinase
- Extra Details:
- This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.
- Shipping Conditions:
- Blue Ice