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E-AB-15907

AGRN Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-15907
Additional Names:
AGRIN,AGRN,Agrin proteoglycan,FLJ45064,OTTHUMP00000044043
Application:
IHC
Concentration:
0.3 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human AGRN
Uniprot:
O00468
Synonyms:
agrin;agrin proteoglycan;CMS8;CMSPPD
Extra Details:
This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ), as identified in mouse knock-out studies. The encoded protein contains several laminin G, Kazal type serine protease inhibitor, and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles, a mutation in this gene was found.
Shipping Conditions:
Blue Ice