E-AB-15856
SOCS7 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-15856
- Additional Names:
- Ash and phospholipase C gamma-binding protein,NAP 4,NAP 4 Fragment,NAP-4,NAP4,NCKAP4,Nck,Nck Ash and phospholipase C binding protein,Nck Ash and phospholipase C gamma binding protein,Nck associated protein 4,Nck-associated protein 4,SH2 domain containing
- Application:
- IHC
- Concentration:
- 0.1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human SOCS7
- Uniprot:
- O14512
- Synonyms:
- NAP-4;NAP4;NCK-associated protein 4;Nck, Ash and phospholipase C binding protein;nck, Ash and phospholipase C gamma-binding protein;NCKAP4;SOCS-7;suppressor of cytokine signaling 7
- Extra Details:
- The protein as regulator signaling cascades probably through protein ubiquitination and/or sequestration. It plays an important role in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA.
- Shipping Conditions:
- Blue Ice