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E-AB-15777

MMP8 Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:
E-AB-15777
Additional Names:
CLG 1,CLG1,Collagenase 1,Collagenase 1 neutrophil,HNC,MMP 8,MMP-8,MMP8,Matrix metallopeptidase 8 (neutrophil collagenase),Matrix metalloprotease 8,Matrix metalloproteinase-8,Mmp8,Neutrophil collagenase,PMNL CL,PMNL collagenase,PMNL-CL,PMNLCL
Application:
IHC, WB
Concentration:
0.4 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human MMP8
Uniprot:
P22894
Synonyms:
CLG1;collagenase 2;HNC;matrix metalloproteinase 8 (neutrophil collagenase);matrix metalloproteinase-8;MMP-8;neutrophil collagenase;PMN leukocyte collagenase;PMNL collagenase;PMNL-CL
Extra Details:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Shipping Conditions:
Blue Ice