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E-AB-15772

c-Fms Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-15772
Additional Names:
C FMS,CD 115,CD115,CD115 antigen,CFMS,CSF 1 R,CSF 1R,CSF-1 receptor,CSF-1-R,CSF1 R,CSF1R,CSFR,Colony stimulating factor 1 receptor,Colony stimulating factor I receptor,EC 2.7.10.1,FIM 2,FIM2,FMS,FMS proto oncogene,FMS protooncogene,HDLS,M-CSF Recept
Application:
WB
Concentration:
0.5 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human CSF1R
Uniprot:
P07333
Synonyms:
BANDDOS;C-FMS;CD115;CD115 antigen;CSF-1 receptor;CSF-1R;CSFR;FIM2;FMS;FMS proto-oncogene;HDLS;M-CSF-R;macrophage colony stimulating factor I receptor;macrophage colony-stimulating factor 1 receptor;McDonough feline sarcoma viral (v-fms) oncogene homolog;proto-oncogene c-Fms
Extra Details:
The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction.
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Blue Ice