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E-AB-15758

LRP5 Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:
E-AB-15758
Additional Names:
BMND1,EVR1,EVR4,HBM,LR3,LRP-5,LRP5,LRP7,Low density lipoprotein receptor related protein 5,Low density lipoprotein receptor related protein 7,Low-density lipoprotein receptor-related protein 5,Lrp5,OPPG,OPS,OPTA1,Osteoporosis pseudoglioma syndrome,VBCH2
Application:
IHC
Concentration:
1.4 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human LRP5
Uniprot:
O75197
Synonyms:
BMND1;EVR1;EVR4;HBM;low density lipoprotein receptor-related protein 5;low density lipoprotein receptor-related protein 7;low-density lipoprotein receptor-related protein 5;LR3;LRP-5;LRP-7;LRP7;OPPG;OPS;OPTA1;PCLD4;VBCH2
Extra Details:
This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.
Shipping Conditions:
Blue Ice