E-AB-15724
PPP1R13L Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-15724
- Additional Names:
- IASPP,Inhibitor of ASPP protein,NFkB interacting protein 1,NKIP1,PPP1R13B-like protein,PPP1R13L,Protein iASPP,RAI,RelA-associated inhibitor,inhibitor of apoptosis stimulating protein of p53,protein phosphatase 1 regulatory (inhibitor) subunit 13 like
- Application:
- IHC, WB
- Concentration:
- 0.6 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human PPP1R13L
- Uniprot:
- Q8WUF5
- Synonyms:
- IASPP;inhibitor of apoptosis stimulating protein of p53;inhibitor of ASPP protein;NFkB interacting protein 1;NFkB-interacting protein 1;NKIP1;PPP1R13B-like protein;protein iASPP;protein phosphatase 1, regulatory (inhibitor) subunit 13 like;RAI;RAI4;relA-associated inhibitor;retinoic acid induced 4
- Extra Details:
- RelA-associated inhibitor is a protein that in humans is encoded by the PPP1R13L gene. Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis. Interacts with RELA NF-kappa-B subunit and with SP1 via its C-terminus part. Interacts with p53/TP53, TP63 and TP73.
- Shipping Conditions:
- Blue Ice