E-AB-15703
GRK2 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-15703
- Additional Names:
- ADRBK1,ARBK1,Adrenergic beta receptor kinase 1,BARK,BARK1,Beta ARK 1,Beta ARK1,Beta adrenergic receptor kinase 1,Beta-ARK-1,Beta-adrenergic receptor kinase 1,FLJ16718,G protein coupled receptor kinase 2,G-protein coupled receptor kinase 2,GRK2
- Application:
- IHC
- Concentration:
- 0.5 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human ADRBK1
- Uniprot:
- P25098
- Synonyms:
- ADRBK1;adrenergic beta receptor kinase 1;BARK1;beta-adrenergic receptor kinase 1;beta-ARK-1;BETA-ARK1;G-protein coupled receptor kinase 2
- Extra Details:
- The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.
- Shipping Conditions:
- Blue Ice