E-AB-15680
GJB6 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-15680
- Additional Names:
- CXB6,Connexin 30,Connexin-30,Cx30,DFNA3,DFNA3B,DFNB1B,ECTD2,ED2,EDH,Gap junct,Gap junction beta 6 protein,Gap junction beta-6 protein,beta 6,beta 6 (connexin 30),ectodermal dysplasia 2,gap junction protein,hidrotic (Clouston syndrome)
- Application:
- IHC
- Concentration:
- 0.4 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human GJB6
- Uniprot:
- O95452
- Synonyms:
- connexin 30;Connexin-30;CX30;DFNA3;DFNA3B;DFNB1B;ECTD2;ectodermal dysplasia 2, hidrotic (Clouston syndrome);ED2;EDH;gap junction beta-6 protein;gap junction protein, beta 6, 30kDa;HED;HED2
- Extra Details:
- Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed by two hemichannels, made up of six connexin proteins assembled in groups. Each connexin protein has four transmembrane segments, two extracellular loops, a cytoplasmic loop formed between the two inner transmembrane segments, and the N- and C-terminus both being in the cytoplasm. The specificity of the gap junction is determined by which connexin proteins comprise the hemichannel. In the past, connexin protein names were based on their molecular weight, however the new nomenclature uses sequential numbers based on which form (alpha or beta) of the gap junction is present. This gene encodes one of the connexin proteins. Mutations in this gene have been found in some forms of deafness and in some families with hidrotic ectodermal dysplasia.
- Shipping Conditions:
- Blue Ice