E-AB-15504
NPR1 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-15504
- Additional Names:
- ANP-A,ANPR-A,ANPRA,ANPa,Atrial natriuretic peptide A type receptor,Atrial natriuretic peptide receptor 1,Atrial natriuretic peptide receptor A,Atrial natriuretic peptide receptor type A,Atrionatriuretic peptide receptor A,GC A,GC-A,Guanylate cyclase
- Application:
- IHC
- Concentration:
- 0.4 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human NPR1
- Uniprot:
- P16066
- Synonyms:
- ANP-A;ANPa;ANPR-A;ANPRA;atrial natriuretic peptide receptor 1;atrial natriuretic peptide receptor type A;atrionatriuretic peptide receptor A;GC-A;guanylate cyclase A;GUC2A;GUCY2A;natriuretic peptide A type receptor;natriuretic peptide receptor A;natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A);NPR-A;NPRA;testicular tissue protein Li 20
- Extra Details:
- Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms . The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides, they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2, MIM 108961). Also see NPR3 (MIM 108962), which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP (MIM 108780) and BNP (MIM 600295), respectively).
- Shipping Conditions:
- Blue Ice