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E-AB-15490

LOX Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-15490
Additional Names:
LYOX,Lysyl oxidase,MGC105112,Protein lysine 6 oxidase,Protein-lysine 6-oxidase,lox
Application:
IHC, WB
Concentration:
0.3 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human LOX
Uniprot:
P28300
Synonyms:
AAT10;Lysyl oxidase;protein-lysine 6-oxidase
Extra Details:
The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.
Shipping Conditions:
Blue Ice