E-AB-15457
TNK2 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-15457
- Additional Names:
- ACK,ACK 1,ACK-1,ACK1,Acetate kinase 1,Acetokinase 1,Activated CDC42 kinase 1,Activated Cdc42 associated kinase 1,Activated p21cdc42Hs kinase,FLJ44758,FLJ45547,TNK 2,TNK2,Tyrosine kinase non receptor 2,Tyrosine kinase non receptor protein 2,p21cdc42Hs
- Application:
- IHC
- Concentration:
- 0.5 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human TNK2
- Uniprot:
- Q07912
- Synonyms:
- ACK;ACK-1;ACK1;activated CDC42 kinase 1;activated Cdc42-associated kinase 1;activated p21cdc42Hs kinase;p21cdc42Hs;tyrosine kinase non-receptor protein 2
- Extra Details:
- This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.
- Shipping Conditions:
- Blue Ice