E-AB-15386
SERPINB8 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-15386
- Additional Names:
- CAP 2,CAP-2,CAP2,Cytoplasmic antiproteinase 2,OTTHUMP00000067000,OTTHUMP00000067001,PI 8,PI-8,PI8,Peptidase inhibitor 8,Protease inhibitor 8 (ovalbumin type),Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 8,Serpin B8,Serpin peptidase
- Application:
- IHC
- Concentration:
- 0.6 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human SERPINB8
- Uniprot:
- P50452
- Synonyms:
- C18orf53;CAP2;cytoplasmic antiproteinase 2;peptidase inhibitor 8;PI-8;PI8;protease inhibitor 8 (ovalbumin type);PSS5;serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 8;serpin B8;serpin peptidase inhibitor, clade B (ovalbumin), member 8
- Extra Details:
- The superfamily of high molecular weight serine proteinase inhibitors (serpins) regulate a diverse set of intracellular and extracellular processes such as complement activation, fibrinolysis, coagulation, cellular differentiation, tumor suppression, apoptosis, and cell migration. Serpins are characterized by well-conserved a tertiary structure that consists of 3 beta sheets and 8 or 9 alpha helices (Huber and Carrell, 1989 [PubMed 2690952]). A critical portion of the molecule, the reactive center loop connects beta sheets A and C. Protease inhibitor-8 (PI8, SERPINB8) is a member of the ov-serpin subfamily, which, relative to the archetypal serpin PI1 (MIM 107400), is characterized by a high degree of homology to chicken ovalbumin, lack of N- and C-terminal extensions, absence of a signal peptide, and a serine rather than an asparagine residue at the penultimate position
- Shipping Conditions:
- Blue Ice