E-AB-15114
HSD3B2 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-15114
- Additional Names:
- HSD3B,HSDB,SDR11E2
- Application:
- IHC
- Concentration:
- 0.2 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human HSD3B2
- Uniprot:
- P26439
- Synonyms:
- 3 beta-HSD type II;3 beta-hydroxysteroid dehydrogenase type II, delta 5-delta 4-isomerase type II, 3 beta-HSD type II;3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2;3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II;3-beta-HSD adrenal and gonadal type;3-beta-HSD II;3-beta-hydroxy-5-ene steroid dehydrogenase;3-beta-hydroxy-Delta(5)-steroid dehydrogenase;delta 5-delta 4-isomerase type II;HSD3B;HSDB;progesterone reductase;SDR11E2;short chain dehydrogenase/reductase family 11E, member 2
- Extra Details:
- The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene.
- Shipping Conditions:
- Blue Ice