HSD17B12 Polyclonal Antibody

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£106.20

Was £118.00

SKU:: E-AB-15104
Additional Names:: 12,17 beta HSD 12,17 beta hydroxysteroid dehydrogenase 12,17-@beta-HSD XII,17-@beta-hydroxysteroid dehydrogenase XII,17-beta-HSD 12,17-beta-hydroxysteroid dehydrogenase 12,17beta HSD type 12,3 ketoacyl CoA reductase,3-,3-ketoacyl-CoA reductase,short chain
Application:: IHC, WB
Concentration:: 0.3 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant protein of human HSD17B12
Uniprot:: Q53GQ0
Synonyms:: 17-beta-HSD 12;17-beta-hydroxysteroid dehydrogenase 12;17beta-HSD type 12;3-ketoacyl-CoA reductase;estradiol 17-beta-dehydrogenase 12;KAR;SDR12C1;short chain dehydrogenase/reductase family 12C member 1;steroid dehydrogenase homolog;very-long-chain 3-oxoacyl-CoA reductase
Extra Details:: This gene encodes a very important 17beta-hydroxysteroid dehydrogenase (17beta-HSD) that converts estrone into estradiol in ovarian tissue. This enzyme is also involved in fatty acid elongation. Catalyzes the transformation of estrone (E1) into estradiol (E2), suggesting a central role in estrogen formation. Its strong expression in ovary and mammary gland suggest that it may constitute the major enzyme responsible for the conversion of E1 to E2 in women.