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E-AB-15035

FHIT Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-15035
Additional Names:
AP3A hydrolase,AP3A hydrolase fragile site 3p14.2,AP3Aase,Bis 5' adenosyl triphosphatase,Bis(5' adenosyl) triphosphatase,Diadenosine 5' 5''' P1 P3 triphosphate hydrolase,Dinucleosidetriphosphatase,FRA 3B,FRA3B,Fragile histidine tri,Fragile histidine triad
Application:
IHC
Concentration:
0.6 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human FHIT
Uniprot:
P49789
Synonyms:
AP3A hydrolase;AP3Aase;bis(5'-adenosyl)-triphosphatase;diadenosine 5',5'''-P1,P3-triphosphate hydrolase;dinucleosidetriphosphatase;FRA3B;Fragile histidine triad protein
Extra Details:
This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene.
Shipping Conditions:
Blue Ice