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E-AB-15017

FAP Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:
E-AB-15017
Additional Names:
170 kDa melanoma membrane bound gelatinase,170 kDa melanoma membrane-bound gelatinase,DPPIV,FAP,FAPA,Fibroblast activation protein alpha,Integral membrane serine protease,SEPR,Seprase
Application:
IHC
Concentration:
0.6 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human FAP
Uniprot:
Q12884
Synonyms:
170 kDa melanoma membrane-bound gelatinase;dipeptidyl peptidase FAP;DPPIV;FAPA;FAPalpha;Fibroblast activation protein alpha;gelatine degradation protease FAP;integral membrane serine protease;post-proline cleaving enzyme;prolyl endopeptidase FAP;seprase;Serine integral membrane protease;SIMP;surface-expressed protease
Extra Details:
The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis.
Shipping Conditions:
Blue Ice