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E-AB-14979

EIF3H Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:
E-AB-14979
Additional Names:
EIF3H,EIF3S3,Eukaryotic translation initiation factor 3 subunit 3,Eukaryotic translation initiation factor 3 subunit H,MGC102958,eIF-3-gamma,eIF3 gamma,eIF3 p40,eIF3 p40 subunit,eIF3h
Application:
IHC, WB
Concentration:
0.8 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human EIF3H
Uniprot:
O15372
Synonyms:
eIF-3-gamma;eIF3 p40 subunit;eIF3-gamma;eIF3-p40;EIF3S3;eukaryotic translation initiation factor 3 subunit 3;eukaryotic translation initiation factor 3 subunit H;eukaryotic translation initiation factor 3, subunit 2 (beta, 36kD);eukaryotic translation initiation factor 3, subunit 3 (gamma, 40kD);eukaryotic translation initiation factor 3, subunit 3 gamma, 40kDa
Extra Details:
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Shipping Conditions:
Blue Ice