E-AB-14947
DLD Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-14947
- Additional Names:
- DLDD,DLDH,Dehydrogenase complex,Diaphorase,Dihydrolipoamide dehydrogenase,Dihydrolipoyl dehydrogenase,Dihydrolipoyl dehydrogenase mitochondrial,E3,E3 branched chain aplha-keto acid,E3 component,E3 component ,E3 component of pyruvate dehydrogenase,dld
- Application:
- IHC
- Concentration:
- 0.6 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human DLD
- Uniprot:
- P09622
- Synonyms:
- diaphorase;Dihydrolipoamide dehydrogenase;dihydrolipoyl dehydrogenase, mitochondrial;DLDD;DLDH;E3;E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex;epididymis secretory sperm binding protein;GCSL;glycine cleavage system L protein;glycine cleavage system protein L;LAD;lipoamide dehydrogenase;lipoamide reductase;lipoyl dehydrogenase;OGDC-E3;PHE3
- Extra Details:
- This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, the encoded protein functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism. However, as a monomer, this protein can function as a protease. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. Alternative splicing results in multiple transcript variants.
- Shipping Conditions:
- Blue Ice