E-AB-14896
CRK Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-14896
- Additional Names:
- Adapter molecule crk,Avian sarcoma virus CT10 (v crk) oncogene homolog,CRK,CRK isoform 2,CRK isoform II,CRKII,FLJ38130,OTTHUMP00000115366,OTTHUMP00000198330,Proto oncogene C crk,Proto-oncogene C-crk,p38,v crk avian sarcoma virus CT10 oncogene homolog
- Application:
- IHC
- Concentration:
- 0.4 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human CRK
- Uniprot:
- P46108
- Synonyms:
- adapter molecule crk;CRKII;p38;proto-oncogene c-Crk;v-crk avian sarcoma virus CT10 oncogene homolog;v-crk sarcoma virus CT10 oncogene-like protein
- Extra Details:
- This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.
- Shipping Conditions:
- Blue Ice