CENPC Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:: E-AB-14864
Additional Names:: CENP-C,CENP-C 1,CENPC,CENPC1,Centromere autoantigen C,Centromere autoantigen C1,Centromere protein C,Centromere protein C 1,ICEN7,Interphase centromere complex protein 7,MIF2,hcp-4
Application:: IHC
Concentration:: 0.6 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant protein of human CENPC
Uniprot:: Q03188
Synonyms:: CENP-C;CENP-C 1;CENPC1;centromere autoantigen C;centromere autoantigen C1;centromere protein C;centromere protein C 1;hcp-4;interphase centromere complex protein 7;MIF2
Extra Details:: Centromere protein C 1 is a centromere autoantigen and a component of the inner kinetochore plate. The protein is required for maintaining proper kinetochore size and a timely transition to anaphase. A putative pseudogene exists on chromosome 12. Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres.